This trial will investigate whether patiens admitted with an acute exacerbation of chronic
obstructive lung disease and pulmonary hypertension will benefit from a targeted
Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms
An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.
An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.
Searching Both is inclusive of interventional and observational studies.
This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.
Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.
Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.
Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.
Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.
The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.
The person who is responsible for the scientific and technical direction of the entire clinical study.
Category of organization(s) involved as sponsor (and collaborator) supporting the trial.
The disease, disorder, syndrome, illness, or injury that is being studied.
During admittance due to acute exacerbation of chronic obstructive lung disease will patience
have an echocardiography to examine their pulmonary pressure. If patient have a tricuspidal
return gradient above 40 mmHg, they will receive treatment with a
No Intervention: Control
Patients in the control group will receive standard care.
Active Comparator: Sildenafil
Patients in the Sildenafil group will receive standard care and targeted Sildenafil-treatment.
Drug: - Sildenafil
Sildenafil in standard dosage
If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.
Not yet recruiting
Bispebjerg University Hospital
Jens-Ulrik Jensen, MD, PhD
Christian B Laursen, Prof.