The aim of this study is to investigate the frequency and implications of pulmonary
hypertension in lung cancer patients. To do so, data will be collected from all lung cancer
patients at the university hospital Giessen. All data will be analyzed for possible hints of
pulmonary hypertension as a comorbidity in lung cancer patients. All information will be
generated from the regular guidelines based course of treatment and there will be no
interventions. This study will serve as a prospective register for all lung cancer patients
treated at the university hospital Giessen.
Giessen Pulmonary Hypertension Registry and Biobank
Pediatric idiopathic pulmonary hypertension has significant morbidity and mortality. An ever
expanding body of knowledge indicates the important contribution of inflammation to
pathogenesis and successful treatment with glucocorticoids. Over the last several years the
investigators have utilized steroids in patients with severe pulmonary hypertension as part
of a treatment regimen. These basic science studies possibly identifies a biochemical
etiology for the development of disease and may also be impacted by the administration of
steroids. Additionally, there is a commercially available assay which tests for all of the
A heart catheterization is a diagnostic heart procedure used to measure pressures and take
pictures of the blood flow through the heart chambers. Magnetic resonance imaging (MRI)
fluoroscopy shows continuous pictures of the heart chambers that doctors can watch while they
work. Researchers want to test this procedure with catheterization tools routinely used in
x-ray catheterization called guidewires. Guidewires will help move the heart catheter through
the different heart chambers. Guidewires are usually considered unsafe during MRI because MRI
can cause a guidewire to heat while inside the blood vessels and heart....
Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by obstruction of the
pulmonary vasculature by residual organized thrombi, leading to increased pulmonary vascular
resistance (PVR), progressive pulmonary hypertension, and right heart failure.
Medical therapy and balloon angioplasty (BPA) are effective treatment alternatives in
lowering pulmonary pressures and increasing pulmonary flow.
The aim of this study is to assess the hemodynamic effects of BPA or medical therapy on the
pressure-flow relationship in the pulmonary vasculature and the pulmonary vascular
The goal of this observational study is to learn about heart function and high lung blood
pressure in patients with heart failure. The main question[s] it aims to answer are whether
we can improve the ability to predict patients who will have complications after they receive
treatment including heart transplant and left ventricular assist devices.
Our hypothesis is that optimal treatment of the dysfunctional metabolic pathways which
underlie PAH will improve pulmonary vascular function and consequences of the disease.
This is a prospective longitudinal cohort study to determine the value of HRV obtained using
noninvasive actigraphy to quantify the response to pulmonary vasodilator therapy in newly
diagnosed PAH patients
The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP)
129Xe gas MRI for regional assessment of pulmonary function.
Some patients who have blood clots come down with a life-threatening condition known as
Chronic Thromboembolic Pulmonary Hypertension (CTEPH), which is high blood pressure only in
the arteries of the lungs. This study seeks to understand more about the genetics causes of
CTEPH by obtaining blood samples and examining family histories.